Adapted from BMJ 5th April 2025
A double blind randomised controlled trial of Vitamin D has shown significant reductions in progression of early multiple sclerosis.
An acute first episode such as optic neuritis or transverse myelitis is known as clinically isolated syndrome typical for multiple sclerosis (CIS).
316 people with CIS who had vitamin D levels below 100 nmol/L were randomised to 100,000 IU of colecalciferol or placebo every two weeks.
After two years the rates of disease activity, either clinically or on MRI were seen in 60.3% of those who had had the Vitamin D and 74.1% of the placebo group.
Diabetes Diet 