
Adapted from BMJ 24 Feb 2024
A randomised controlled trial by Mikko Raisanen in Finland compared treatments for Dupuytren’s contracture.
This condition is common in those of Viking ancestry. Famous afflicted people include Ronald Reagan, Margaret Thatcher and Frank Sinatra.
Thickening and tightening of the tendons in the palms of the hands occurs. Progression is usually slow, but as the pinky finger and others become unable to extend, it can cause real difficulty in dressing and holding objects.
Three treatments were compared: surgery, needle fasciotomy and collagenase injections.
At the three month point, all seemed equally successful with 70% improved considerably, but after two years, surgery was 78% effective compared to 50% and 65% respectively.
Diabetics are prone to this condition too, as tendon glycation worsens the problem.