Relugolix is a new drug for endometriosis

Photo by Polina Zimmerman on Pexels.com

Adapted from BMJ 22-29 March 2025

Nice has approved a new daily pill for the treatment of endometriosis. It contains relugolix, estradiol, and norethisterone.

Patients must be of reproductive age and have had medical or surgical treatment but are still symptomatic.

The new pill works on a block and replace method. Relugolix blocks the woman’s own hormones that affect endometriosis and supplies a steady dose of oestrogen and progestogen to replace them.

Users take it at home and it does not need regular clinic visits.

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