Keep safe when cycling

cyclist

Reflective jackets are a great safety aid for cyclists riding in the dark, if they have them and  wear them consistently. A possible way to overcome a cyclists reluctance to wear the said jacket, say for example if they think to themselves, “I’ll be back before it gets dark or it’s too warm for my jacket” is to take the decision out of the equation.

Researchers have found that reflective tape attached to the rear frame of the bike and pedal cranks does the job of increasing visibility just as well as jackets do, but without any active behaviour required of the cyclist.

“Reflective tape is highly recommended to complement front and back lights in bicycle riding at night”, they conclude.

Human Factors, 2016, doi:10.177/001872081667145

Adapted from article in Human Givens Volume 24 No 1 2017

BBC – Hidden disabilities: Pain beneath the surface

help-686323_960_720Hidden disabilities: Pain beneath the surface

Imagine having to inject yourself thousands of times over the course of your lifetime, but never talking about it to anyone.

Many people live with hidden disabilities – conditions which don’t have physical signs but are painful, exhausting and isolating. Sympathy and understanding from others can often be in short supply.

Georgia Macqueen Black has Type 1 Diabetes.

She was diagnosed at the age of 11.

Type 1 Diabetes cannot be seen until I take out my insulin pen and inject myself, but the mechanical parts – blood tests and injections – are only the surface layers of what I have to manage.

Someone may see me inject, but there’s an isolating exhaustion I take with me afterwards. There will always be another injection and it can generate a disconnection between myself and other people.

Every day I gather the willpower to be a “good” diabetic, but when I follow the rules and still have high blood sugar I feel alone. It makes me feel foggy with a limited ability to concentrate. And the side-effects of too much or too little sugar in your blood can lead to you turning in on yourself.

The biggest challenge is accepting the monotony of managing diabetes. There are days when I’m tired of having a weaker immune system – a lesser known side-effect of diabetes – or when I find lumps under my skin from injections, but then I have to put those feelings to one side and carry on.

Some people might not think diabetes deserves the label “disability”, but if unmanaged it affects my ability to carry out tasks and I have to think how exercise, stress or dehydration will impact my blood sugar levels.

I often worry about how life will be when I’m older. This feeling of uncertainty hangs over me from time to time, and can make me feel lonely and a bit lost.

But I know there’s a silent solidarity out there. Someone with an impairment could be having a day where everything has become derailed and they feel ill, but I bet you they won’t show it. It’s that resilience that I really connect to.

Top tips on hidden disabilities

 

  • There’s so much mental labour involved so if I seem distracted it’s probably because of that
  • Believe me when I ask for help. Just because I don’t look like I need assistance, doesn’t mean I’m OK
  • Respect priority seats and wheelchair spaces on public transport
  • Listen to access requirements with an open mind – often small changes make a huge difference
  • Ask for what you need – in asking for help you don’t have to pretend to be someone else

 

Produced by Beth Rose

BBC Disabilties 5.7.17

Fittoservegroup: Low Carb Keto Quiche

Grandma's_Quiche_in_bakeware_pan

Low Carb Keto Quiche

by fittoservegroup

 

I decided to make the crust for this quiche out of coconut flour to once again benefit those who have nut allergies or simply want to reduce their carbs further. I hope this keto quiche inspires you to roll up your sleeves and start creating delicious low carb keto foods for you and your loved ones.

Remember you can always customize this quiche to make it your own. Add or substitute any of the filling items just make sure you keep the eggs and water ratio the same.

Enjoy in good health!

Low Carb Keto Quiche

Crust Ingredients

½ cup (1 stick of butter melted and cooled)

2 large eggs

½ teaspoon sea salt

¾ cup coconut flour

1 teaspoon of sugar substitute (I use Swerve)

Crust Instructions

1.    Mix all the ingredients of the low carb crust just until dough forms.

2.    Roll out dough between two sheets of parchment paper. Set aside.

3.    Transfer crust into a 9 inch, pie pan. Being careful to smooth out any cracks.

4.    Bake at 350 degrees in a pre-heated oven for 15- 20 minutes and set aside to cool.

Quiche Filling

 6 eggs

2 tablespoons of water

1 ½ ounces of Swiss cheese thinly sliced

2 teaspoons of fresh parsley finely minced

¼ cup of finely minced fresh onions (I like to brown mine before adding to the filing for extra flavor)

6 slices of cooked bacon roughly chopped

1 teaspoon of sea salt

½ teaspoon of black pepper

Quiche Instructions

1.    Add the quiche filling and bake at 350 for 25- 30 minutes until the quiche is fully cooked.

2.    Allow to cool slightly before slicing and serving.

3.    Can be eaten hot or at room temperature.

Total Net Carbs per slice 2.9

 

Why do some consultations go wrong and what can we do about it?

elephant.jpg

One in seven consultations are described as difficult by the doctors doing them. Why this happens can be grouped into several categories: patient, doctor, disease and system. More than one factor may contribute in any consultation.

Patients can come across as uncooperative, hostile, demanding, disruptive and unpleasant. Of course the patient may think exactly the same thing about the doctor! Patients may have unrealistic expectations or be unwilling to take responsibility for their health.

Doctors may be in sub-optimal states even before the consultation has started. They can be hungry, angry, late or tired. Their personal lives may be a mess. Their personality may clash with the patients. They may have pre-conceived ideas about the patient which handicaps the consultation before the patient even opens their mouth.

Some conditions are particularly challenging to deal with. These include chronic pain, ill -defined diagnoses and those with little prospect of improvement. Straightforward conditions where there is a recognised pathway of management broadly understood by both doctor and patient are much easier to deal with.

Limited resources, finances, support, interruptions and particularly time pressures all contribute to the difficulties experienced by doctors.

Difficult interactions with patients can take up a disproportionate amount of the doctor’s time, resources and emotional energy. They can cause the doctor to feel stress, anxiety, anger and helplessness and can lead to a dislike of the patient and the use of avoidance strategies. All this compromises the doctor’s ability to provide good care and can lead to increased mistakes which are bad for both doctor and patient alike.

A difficult interaction makes both parties feel frustrated and dissatisfied and may result in a breakdown of trust. The patient is then likely to seek another doctor in the practice or at the hospital and this uses up more precious health care resources.

A doctor who stops listening to patients, argues, talks over them and interrupts them does nothing to get out of the downward spiral that occurs in these consultations. Instead, these other suggestions, which may be made by either doctor or patient can help set things right again.

The first thing to do is to recognise when these difficult consultations arise and instead of getting sucked into the “I’m right and you’re wrong” game, take a step back and try to say what the problem is.

A doctor may say, “ We both have very different view about how your symptoms should be investigated and that is causing some difficulty between us. Do you agree?”  A patient may say, “We both seem to have very different views about the optimal number of blood sugar tests that a diabetic needs to do. Do you agree?”

This approach names the elephant in the room and avoids casting blame, fun though that sometimes is. It externalises the problem from both the patient and the doctor and creates a sense of shared ownership. Verbalising the difficulty is the gateway to working towards a solution.

Sometimes a person who is coming across as angry and abusive may be highly anxious about for example a terminally ill partner.  A doctor can say,  “You seem to me to be very angry about this.  Tell me more about this.”  It is important to listen to what the patient says, because if the patient really feels that they have been heard they are likely to calm down.

Sometimes what the patient wants really is unreasonable. A doctor may have to be clear about what is and is not acceptable sometimes. It is useful for all members of the practice to have consistent rules regarding such things as prescribing or late appointments. The way to explain this could be, our practice has a policy about this matter and the policy is…..

Doctors and patients will often have different ideas on issues such as diagnosis, investigations, and management options. Sometimes there seems to be no common ground which is often the result of unrealistic expectations.  Dr Google and The Daily Mail may have something to do with this.  If both can strive to achieve some common ground difficulties usually diminish.

A solution focused process helps the patient feel included and that they are not being abandoned. Asking them to come up with different options can take some of the burden off of the doctor.

 

Adapted from article by Marika Davies, medico legal adviser, Medical Protection Society, London.

Published in BMJ 3 August 2013

Are you doing what matters most to you?

mum and dad

This amusing article was spotted by psychologist Ron Friedman. Are you spending your time on what really matters?

 

The Tail End
This is one of the most compelling articles I’ve read in a while. It’s a simple concept, yet chances are, it will change the way that you view life (and perhaps even improve your relationship with your parents).

Ron Friedman

 

Anal injuries in Childbirth: A new charity for this rarely discussed problem

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Adapted from Anne Gulland’s interview with surgeon Michael Keighley published in BMJ  25 March 2017.

About one in ten first time mothers who give birth vaginally can develop some sort of anal incontinence. This can lead to soiling, passing wind when you’d rather not, and needing a toilet urgently.

Despite the number of women affected it is rarely talked about. Some women feel trapped in their homes and hide dirty sheets from their partners. Returning to work is a difficulty too.

If the matter has not resolved in a few months surgery is usually required. Even then, this tends to be a patch up job, as getting normal anal function back is difficult. A woman may be able to hold stool in for say three or four minutes after surgery compared to one minute before this.  As the years go on however, anal function can deteriorate again, especially after the menopause.

A study is being done by the Royal College of Obstetricians and Gynaecologists and the Royal College of Midwives to try to get women to hold back in the second stage of labour as the baby’s head is being delivered. Giving a bit more time for the perineum to stretch, rather than just pushing the baby out, can reduce anal tears from 8% to 3%.

If anal tears are detected immediately and repaired by an obstetrician at the time, the success rate is better for the woman. If the tears are left, more scar tissue develops, and this impairs the result of future surgery.

The name of the new charity is: masic.org.uk

 

Susan Pierce Thompson: How to be happy, thin and free

the-3-huge-mistakes-report

This March, Susan’s first book, Bright Line Eating: The Science of Living Happy, Thin & Free, arrived in bookstores.

Here’s what she had to say:

Susan, in Bright Line Eating, you argue that the reason so many people struggle with their weight is that the human brain blocks weight loss. How so?

The human brain was designed to keep us stable in a right-sized body. But modern processed foods and the modern pace of life have hijacked various systems in the brain, and the result is that now, in the present-day environment, the brain does indeed block weight loss.

Here’s how: willpower is a finite resource in the brain. And it doesn’t just help us resist temptations or persevere in the face of challenges – it helps us do all kinds of things, like make decisions (e.g., checking email, going shopping), regulate our emotions (e.g., having kids, being in traffic), and regulate our task performance (e.g., working in Excel, giving a presentation).

After a brief period of time doing any of these things, if we start to think it might be a good time to get something to eat, we’re likely to fall into the Willpower Gap.

This is why so many of us order out for pizza or take-out on a Friday night after a long week, irrespective of how sincere we were when we pledged that this time we would stick with our diet until we lost all our excess weight.

In our modern society, the Willpower Gap is waiting for us, nearly always. Most plans of eating implicitly ask you to rely on your willpower to stick with the plan over the long term. The truth about your brain is that that will never work. You need a plan of eating that assumes you have no willpower at all (because, at any given moment, you may not), and works anyway.

To avoid relying on willpower, you suggest people adopt 4 “bright lines” into their eating habits. What are they?

Bright lines are clear, unambiguous boundaries that you don’t cross, no matter what–similar to how a smoker who wants to quit and get healthy throws up a bright line for cigarettes. The four bright lines I recommend are:

  1. No added sugar or artificial sweeteners
  2. No flour of any kind
  3. Eating only at meals–no snacking or grazing
  4. Bounding quantities of food, both to make sure you get enough vegetables, and to make sure you don’t eat too much of everything else.

What’s one thing everyone reading this can do right now to improve their chances of maintaining a healthy weight?

To really bridge the Willpower Gap, start writing down what you’re going to eat for the day in a little journal, ideally right after dinner the night before. Do it religiously until it becomes a habit. The next day, your job is to eat only and exactly that, no matter what. Make sure there’s no sugar or flour in your food plan for the day, and, ideally, stick with three meals a day, because three meals are much more automatizable than five or six.

Within a few weeks these habits will be automatic, and eating the right things, and not the wrong things, will start to be as easy as brushing your teeth.

 

(From original interview by Ron Friedman)

Sheri Colberg: Things that can unbalance your blood sugars

girl with a cold

Physical Activity Is Only One Part of the Equation

 

By Sheri Colberg, Ph.D.

 

Although a single bout of exercise usually improves insulin action for 2 to 72 hours afterward, the effect also depends on how much you eat before, during, and after working out, how you manage your diabetes medications (particularly insulin), your prior control over your blood glucose levels, how much sleep you get, whether you’re stressed out or not, etc. As you can imagine, it’s not easy to manage and predict all of the possible effects of these various things.

Sometimes it feels like stress can override any or all benefits you were supposed to receive from being active. Getting upset, angry, anxious, frustrated, sad, or depressed can basically erase your improvements in insulin action, although on the flip side, working out can also lower many of those negative feelings if you exercise after they occur. Not only is exercise an acute mood enhancer, but it also allows you to get tired enough that you don’t have as much energy to devote to sustaining your negative emotions.

Having a nasty cold last week also reminded me that simply being sick—even moderately so—can really wreak havoc on blood glucose levels. For me, exercising doing anything other than moderate walking is hard when I’m sick, and you really shouldn’t exercise much or intensely when you’re sick anyway or you can make your illness worse.

Exercise acutely lowers the concentration of illness-fighting immune cells in the bloodstream, and simply overtraining can increase your risk of getting colds and the flu. If you normally use exercise to manage your blood glucose levels more effectively and you’re deprived of doing that while sick, you can often find yourself dealing with not just one thing (illness) that can raise your blood glucose, but two at the same time (lack of exercise being the second). On top of that, you may not be sleeping as well as normal because of being sick, and lack of sleep raises insulin resistance as well. Nothing like a simple cold to throw your whole diabetes regimen out of whack!

It’s also so incredibly easy to override the effects of your last workout with food. You may not want to focus on how much/long you have to exercise to expend enough calories to equal what you eat on a daily basis (it’s a whole lot!), but suffice it to say that most people overestimate the impact of their exercise and underestimate the calorie content of the foods. Most people have to walk at least a mile to burn off close to 100 calories. A modest handful of nuts has closer to 200 calories, and get a burger at a fast-food restaurant and you’ll probably take in over 1,000 calories. Just keep in mind that food can easily have an even greater impact on your blood glucose levels unless you’re one of those avid exercisers that exceeds the daily recommended amounts (30 minutes of moderate activity) by exercising hours a day.

If you already exercise regularly, sometimes you fail to get the same glucose lowering effect as someone who is just starting out with training. With training, your body becomes adapted to the activity, which can make fat use higher and blood glucose use lower during the same activity. So, what used to really feel like it revved up your insulin action afterwards may not do much for you anymore, and when you don’t do your usual activities, you pay the price of having to deal with rising blood glucose levels unless you up your medications or cut back your food (or both).

It may sound like I’m trying to talk you out of exercising regularly to help with diabetes management, but really nothing could be farther from the truth. I’m simply warning you that life can throw many different monkey wrenches into your usual responses, so go easy on yourself when you don’t get it right every time. Lose the guilt, and just manage your blood glucose levels the best you can on any given day and stay active for your overall health.

In addition to my educational web site, Diabetes Motion (www.diabetesmotion.com), I also recently founded an academy for fitness and other professionals seeking continuing education enabling them to effectively work with people with diabetes and exercise: Diabetes Motion Academy, accessible at www.dmacademy.com. Please visit those sites and my personal one (www.shericolberg.com) for more useful information about being active with diabetes.

Eric Barker: How to make friends as an adult

friendship gibran

 Originally posted in Welcome to the Barking Up The Wrong Tree weekly update for February 19th, 2017.

This Is How To Make Friends As An Adult: 5 Secrets Backed By Research

Click here to read the post on the blog or keep scrolling to read in-email.

When you were a kid it was a lot easier. In college you almost had to be trying not to make friends. But then you’re an adult. You get busy with work. Your friends get busy with work. People get married. Have kids. And pretty soon being “close” means a text message twice a year.

You’re not alone… Or, actually, the whole point of this is you really may be alone. But you’re not alone in being alone. These days we’re all alone together. In 1985 most people said they had 3 close friends. In 2004 the most common number was zero.

Via Social: Why Our Brains Are Wired to Connect:

In a survey given in 1985, people were asked to list their friends in response to the question “Over the last six months, who are the people with whom you discussed matters important to you?” The most common number of friends listed was three; 59 percent of respondents listed three or more friends fitting this description. The same survey was given again in 2004. This time the most common number of friends was zero. And only 37 percent of respondents listed three or more friends. Back in 1985, only 10 percent indicated that they had zero confidants. In 2004, this number skyrocketed to 25 percent. One out of every four of us is walking around with no one to share our lives with.
Friends are important. Nobody would dispute that. But I doubt you know how very important they are.

So let’s see just how critical friends can be — and the scientifically backed ways to get more of them in your life…

Loneliness Is A Killer

When people are dying, what do they regret the most? Coming in at #4 is: “I wish I had stayed in touch with my friends.”

And neglecting your friends can make those deathbed regrets come a lot sooner than you’d like. When I spoke to Carlin Flora, author of Friendfluence: The Surprising Ways Friends Make Us Who We Are, she told me:

Julianne Holt-Lunstad did a meta-analysis of social support and health outcomes and found that not having enough friends or having a weak social circle is the same risk factor as smoking 15 cigarettes a day.
Maybe your grandparents lived to 100 and you take good care of yourself. You’re healthy. But if you want those years to be full of smiles, you need to invest in friendship. 70% of your happiness comes from relationships.

Via The 100 Simple Secrets of Happy People:

Contrary to the belief that happiness is hard to explain, or that it depends on having great wealth, researchers have identified the core factors in a happy life. The primary components are number of friends, closeness of friends, closeness of family, and relationships with co-workers and neighbors. Together these features explain about 70 percent of personal happiness. – Murray and Peacock 1996
The Grant Study at Harvard has followed a group of men for their entire lives. The guy who led the study for a few decades, George Vaillant, was asked, “What have you learned from the Grant Study men?” Vaillant’s response?

That the only thing that really matters in life are your relationships to other people.
So friendships are really really really important. But maybe you’re not worried. Maybe you have lots of friends. Guess what?

In seven years, half of your close friends won’t be close to you anymore.

Via Friendfluence: The Surprising Ways Friends Make Us Who We Are:

A study by a Dutch sociologist who tracked about a thousand people of all ages found that on average, we lose half of our close network members every seven years. To think that half of the people currently on your “most dialed” list will fade out of your life in less than a decade is frightening indeed.
Ouch. Scared yet? I am.

(To learn an FBI behavior expert’s tips for getting people to like you, click here.)

So what do we do? (No, going back to college is not the answer.) How do we make new friends as adults?

1) The New Starts With The Old

The first step to making new friends is… don’t. Instead, reconnect with old friends:

These findings suggest that dormant relationships – often overlooked or underutilized – can be a valuable source of knowledge and social capital.
Doing this is easy, it’s not scary, they’re people you already have history with, and it doesn’t take a lot of time or work to get to know them. Go to Facebook or LinkedIn for ideas and then send some texts. Boom. You already have more friends.

If you’re going to be strategic, who should your prioritize? You probably met a disproportionate number of your friends through just a handful of people. Those are your “superconnectors.”

Rekindle those relationships. And then ask them if there’s anyone you should meet. Next time you get together, see if that new person can come along. Not. Hard. At. All.

(To learn how to deal with a narcissist, click here.)

But maybe this feels a little awkward. Maybe your friendship muscles have atrophied. Maybe you weren’t great at making friends in the first place. So what really makes people “click”?

2) Listen, Seek Similarity, and Celebrate

Clicking with people is a lot less about you and a lot more about focusing on them. Don’t be interesting. Be interested. And what are the best ways to do that?

Listen, Seek Similarity, and Celebrate.

Studies show being likable can be as easy as listening to people and asking them to tell you more.

And mountains of research show similarity is critical. So when they mention something you have in common, point it out.

Finally, celebrate the positive. When someone talks about the good things in their life, be enthusiastic and encouraging.

Via The Myths of Happiness:

The surprising finding is that the closest, most intimate, and most trusting relationships appear to be distinguished not by how the partners respond to each other’s disappointments, losses, and reversals but how they react to good news.
(To learn more about how to be someone people love to talk to, click here.)

Alright, your superconnectors are making introductions and you’re clicking. But how do you get close to these new people? We’ve all met people we thought were cool… but just didn’t know how to take it to the next level and go from acquaintance to friend. It’s simple, but not necessarily easy…

3) Be Vulnerable

Open up a bit. Don’t go full TMI, but make yourself a little bit vulnerable. Nobody becomes besties by only discussing the weather.

Close friends are what leads to personal discussions. But personal discussions are also what leads to close friends.

Via Click: The Magic of Instant Connections:

Allowing yourself to be vulnerable helps the other person to trust you, precisely because you are putting yourself at emotional, psychological, or physical risk. Other people tend to react by being more open and vulnerable themselves. The fact that both of you are letting down your guard helps to lay the groundwork for a faster, closer personal connection.
Close friends have a good “if-then profile” of each other. Once you have an idea of “if” someone was in situation X, “then” they would display behavior Y, that means you’re really starting to understand them. And this leads to good friendships:

People who had more knowledge of their friend’s if-then profile of triggers had better relationships. They had less conflict with the friend and less frustration with the relationship.
How many close friends do you need? If we go by the science, you want to aim for at least five.

Via Finding Flow: The Psychology of Engagement with Everyday Life:

National surveys find that when someone claims to have five or more friends with whom they can discuss important problems, they are 60 percent more likely to say that they are ‘very happy.’
(To learn the lazy way to an awesome life, click here.)

So you have new friends. Awesome. Now how do you not screw this up?

4) Don’t Be A Stranger

First and foremost: make the time. What’s the most common thing friends fight about? Time commitments.

Via Friendfluence: The Surprising Ways Friends Make Us Who We Are:

Daniel Hruschka reviewed studies on the causes of conflict in friendship and found that the most common friendship fights boil down to time commitments. Spending time with someone is a sure indicator that you value him; no one likes to feel undervalued.
You need to keep in touch. (Remember: not keeping in touch is how you got into this problem in the first place.)

If you want to stay close friends with someone, how often do you need to check in? Research says at least every two weeks.

(To learn the four rituals neuroscience says will make you happy, click here.)

So even if you need to set a reminder on your calendar, check in every two weeks. But, actually, there’s a better way to make sure you don’t forget…

5) Start A Group

Denmark has the happiest people in the world. (I’m guessing Hamlet was an exception.) Why are Danes so happy? One reason is that 92% of them are members of some kind of social group.

Via Engineering Happiness: A New Approach for Building a Joyful Life:

The sociologist Ruut Veenhoven and his team have collected happiness data from ninety-one countries, representing two-thirds of the world’s population. He has concluded that Denmark is home to the happiest people in the world, with Switzerland close behind… Interestingly enough, one of the more detailed points of the research found that 92 percent of the people in Denmark are members of some sort of group, ranging from sports to cultural interests. To avoid loneliness, we must seek active social lives, maintain friendships, and enjoy stable relationships.
And what’s the best way to make sure you’re in a group? Start one. That makes it a lot easier to stay in touch and a lot easier to manage those big 5 friendships with 20% of the effort.

A weekly lunch. A monthly sewing circle. A quarterly movie night. Whatever works. Friends bring friends and suddenly it’s not so hard to meet cool new people. And who does everyone have to thank for this? You.

And make the effort to keep that group solid for everyone. Many studies show older people are happier. What’s one of the reasons? They prune the jerks out of their social circles:

Other studies have discovered that as people age, they seek out situations that will lift their moods — for instance, pruning social circles of friends or acquaintances who might bring them down.
(To learn the 6 rituals ancient wisdom says will make you happy, click here.)

Alright, popular kid, we’ve learned a lot. Let’s round it up and find out how to keep your new friendships alive over the long haul…

Sum Up

Here’s how to make friends as an adult:

  • The new starts with the old: Touch base with old friends and leverage your superconnectors.
  • Listen, seek similarity and celebrate: Don’t be interesting. Be interested.
  • Be vulnerable: Open up a bit. Form an “if-then” profile.
  • Don’t be a stranger: Check in every two weeks, minimum.
  • Start a group: Things that are habits get done. So start a group habit.

What does Carlin Flora, author of Friendfluence, say is the number one tip for keeping friendships alive?

Reach out to your good friends and tell them how much they mean to you. It’s just not something we’re accustomed to doing. It’ll make you feel great, it’ll make them feel great and it will strengthen the bond between you. Be more giving to the friends you already have. People in romantic relationships always celebrate anniversaries, yet you might have a friend for 15 years and you’ve probably never gone out to dinner and raised a glass to that. We need to cherish our friendships more.
Okay, you’re done reading. Time to start doing. Reach out to a friend right now. Send them this post and let’em know you want to get together.

Listen to what they’ve been up to. Celebrate their good news. Offer to help them out with something.

After all, that’s what friends are for.

Please share this. (It’s a very friendly thing to do.) Thank you!

 

Thanks for reading!
Eric
PS: If a friend forwarded this to you, you can sign up to get the weekly email yourself here.

What’s new in the prevention of the microvascular complications of diabetes?

Apart from blood sugar control what’s new in the prevention of the microvascular complications of diabetes?

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Retinopathy

At diagnosis, 10.5% of type two diabetics already have retinopathy. New research has shown that severe proliferative diabetic neuropathy can be predicted by measuring the size of retinal blood vessels, but this is still being developed in research centres. It could become a part of the usual screening process in the future.

Lowering blood pressure in those who are hypertensive by at least 10 points, can reduce the onset of retinopathy but does not affect the rate at which it develops into proliferative retinopathy. What does seem to work is the use of oral Fenofibrate.

Laser photocoagulation reduces the rate of progression of proliferative retinopathy and the onset of severe visual loss. Direct injection of drugs that inhibit Vascular Endothelial Growth Factor such as pegaptanib, ranibizumab, and bevacizumab also help but they are less freely available, due to cost.

dialysis

Nephropathy

NICE recommend spot urinary albumin to the creatinine ratio and glomerular filtration rate on diagnosis and then yearly. If the rate is raised on 2 out of 3 samples within six months then nephropathy is confirmed and the severity graded.

Blood pressure targets are 140/90 for those without nephropathy and 130/80 for those that have it. Some people may benefit from lower blood pressure targets of 120 systolic such as Asian, Hispanic and African American populations.

Both ACE inhibitors and Sartans (ARB) reduce nephropathy and ACE inhibitors also improve all- cause mortality.  These drugs are the first choice for most diabetics when prescribing anti-hypertensives.

Early referral to a nephrologist showed an improvement in interventions and mortality rates. There was also a small improvement in kidney function when the new drug Dapagliflozin was used.

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Neuropathy

There are other causes of neuropathy that may need to be considered before diabetic neuropathy is diagnosed. These are: alcohol, chemotherapy, vitamin B12 deficiency, hypothyroidism, renal disease, paraneoplastic syndromes due to eg multiple myeloma and bronchogenic carcinoma, HIV infection, chronic inflammatory demyelinating neuropathy, inherited neuropathies and vasculitis.

A new Japanese drug Epalrestat improved diabetic neuropathy but did not improve autonomic neuropathy.

There was insufficient evidence to show that exercise, pulse infrared light therapy, education about foot ulceration and complex interventions such as combining patient education, podiatry care, foot ulceration assessment, motivational coaching to provide self- care, worked or not.

 

BMJ 4th February 2017 Willy Marcos Valencia and Hermez Florez from Miami Florida.

 BMJ 2017;356:i6505